Cinnamic acids and derivatives
Medchemexpress LLC 4-Acetoxycinnamic ac 100mg
4-Acetoxycinnamic acid is an acetate ester obtained by the formal condensation of the hydroxy group of trans-4-coumaric acid with acetic acid 4-Acetoxycinnamic acid is a member of cinnamic acids and a member of phenyl acetates 4-Acetoxycinnamic acid derives from a trans-4-coumaric acid[1]
Medchemexpress LLC Ginkgolic acid | 20261-38-5 | 99.9% | 320.47 | C20H32O3 | 10 MG
Ginkgolic acid (C13:0) is a natural small molecule used in research as an anti-cariogenic agent and a PI3Kδ inhibitor; it also exhibits antibacterial and anti-parasitic activity and can inhibit mast cell degranulation.
- Chemical formula C20H32O3.
- Molecular weight 320.47 g·mol-1.
- CAS number 20261-38-5.
- Purity 99.92%.
- Physical form solid suitable for analytical and research use.
- Available in milligram pack sizes for research (for example, 1 mg, 5 mg, 10 mg).
TARGETMOL CHEMICALS INC REFAMETINIB R ENANTIOMER 5MG
Also available in 1 mg 10 mg 25 mg 50 mg 100 mg 500 mg and bulk. Please contact Fisher for quotes. Refametinib R enantiomer (RDEA119 R enantiomer) is an MEK inhibitor with an EC50 of 2.0-15 nM.Refametinib (R enantiomer) has anticancer activity and can be used in cancer research. purity: 99%
TARGETMOL CHEMICALS INC UMBRALISIB R-ENANTIOMER 5MG
Also available in 1 mg 2 mg 10 mg 25 mg 50 mg 100 mg 1 mL 10 mM (in DMSO) and bulk. Please contact Fisher for quotes. Umbralisib R-enantiomer (RP5264 R-enantiomer) is a delta inhibitor of PI3K and a less active enantiomer of TGR-1202. The IC50 of Umbralisib R-enantiomers against (delta)PI3 kinase is at least 20 times lower than that of the inhibitors against other PI3K isoforms (A (beta) and (gamma)). purity: 95%
Medchemexpress LLC cis-Ferulic acid 4-O-β-D-glucopyranoside | 94942-20-8 | 356.32 | 1 MG
cis-Ferulic acid 4-O-β-D-glucopyranoside (compound 7) is a phenolic glycoside that can be isolated from Nitraria sibirica. It exhibits antioxidant activity and a potent inhibitory effect on Phosphatase PTP1B.
- Phenolic glycoside
- Isolated from Nitraria sibirica
- Exhibits antioxidant activity
- Potent inhibitory effect on Phosphatase PTP1B
Medchemexpress LLC 3-Methylcinnamic acid | 3029-79-6 | 99.77% | C10H10O2 | 5 G
3-Methylcinnamic acid is a drug intermediate utilized in the synthesis of various active compounds. This product is strictly for research use only and is not intended for patient administration. Careful handling and storage are recommended to maintain product integrity and safety.
- Store powder at -20°C for up to 3 years or at 4°C for 2 years.
- When in solvent, store at -80°C for 6 months or at -20°C for 1 month.
- Avoid breathing dust, fume, gas, mist, vapors, or spray.
- Wash hands thoroughly after handling.
- Use only outdoors or in a well-ventilated area.
- Wear appropriate protective equipment including gloves, clothing, and eye/face protection.
- May cause irritation to skin, eyes, and respiratory tract.
eMolecules 2-Fluorocinnamic acid | 451-69-4 | MFCD00004370 | 25g
Matrix Scientific | 2-Fluorocinnamic acid | 25g | 389714243 | 4179 | 98.000 | 451-69-4 | MFCD00004370 | 166.151 | C9H7FO2
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Apexbio Technology LLC Entacapone 130929-57-6 10mM (in 1mL DMSO)
Entacapone (CAS 130929-57-6) is a selective second-generation inhibitor of catechol-O-methyltransferase (COMT) It demonstrates potent inhibition of total COMT in mouse liver with reported IC50 and Ki values of 20 1 nM and 10 7 nM respectively In rat models IC50 values for soluble COMT and membrane-bound COMT are 14 3 nM and 73 3 nM Entacapone is primarily utilized in research as an adjunct to levodopa and dopa decarboxylase inhibitor regimens in Parkinson s disease studies given its ability to suppress the formation of 3-O-methyldopa thereby enhancing levodopa bioavailability and prolonging its pharmacological effect
Apexbio Technology LLC Tyrphostin A1 2826-26-8 50mg
Tyrphostin A1 (CAS 2826-26-8) is a small molecule inhibitor targeting tyrosine kinase activity specifically involved in disrupting intracellular signaling pathways in immune cells It has been shown to interfere with CD40 ligand-induced signaling resulting in suppressed interleukin-12 (IL-12) secretion by macrophages and reduced differentiation of antigen-induced T helper 1 (Th1) cells Tyrphostin A1 is widely utilized in studies investigating cell-to-cell signaling immune response modulation and the mechanisms underlying inflammatory processes particularly in the context of autoimmune disease models
Medchemexpress LLC Ferulic acid 4-O-sulfate | 86321-29-1 | 98.07% | 274.25 | 100 MG
Ferulic acid 4-O-sulfate, also known as Ferulic acid 4-sulfate, is a metabolite of Ferulic acid that has been observed to relax arteries and decrease blood pressure in mice.
- In vitro: This compound, at concentrations ranging from 0.1 to 30 μM, elicited significant concentration-dependent relaxations in the aorta, femoral, and saphenous arteries of mice.
- In vivo: When administered intravenously to male Swiss mice at dosages of 16.13 and 161.3 μg/kg, ferulic acid 4-O-sulfate demonstrated the ability to relax arteries and lower blood pressure, with a significant decrease in mean arterial pressure (MAP) observed immediately post-injection.
Medchemexpress LLC Tyrphostin AG 112 | 144978-82-5 | 98.3% | 236.23 | 25 MG
Tyrphostin AG 112 is an EGFR phosphorylation inhibitor intended for research use only. It inhibits EGFR in human A431 cells with an IC50 of 0.1 μM.
- EGFR phosphorylation inhibitor
- Inhibits EGFR in human A431 cells with an IC50 of 0.1 μM
- For research use only
- Appears as a light yellow to yellow solid
TARGETMOL CHEMICALS INC LASSBio-1135 1MG
Also available in 5 mg, 10 mg, 25 mg, 50 mg, 100 mg and bulk. Please contact Fisher for quotes. LASSBio-1135 is an orally effective antagonist of TRPV1 and inhibitor of TNF-alpha production. Purity 98.43%