Cinnamic acids and derivatives
Aobchem (5-Chloro-2-fluoro-3-(methoxycarbonyl)phenyl)boronic acid | 95% | C8H7BClFO4 | 500mg
(5-Chloro-2-fluoro-3-(methoxycarbonyl)phenyl)boronic acid | 95% | C8H7BClFO4 | 500mg
Ambeed trans trans 4Pentylphenyl 4 p
(trans,trans)-4-Pentylphenyl 4'-propyl-[1,1'-bi(cyclohexane)]-4-carboxylate, 84078-44-4, 97%
eMolecules 400878-24-2 | 2'-(4-Fluorobenzyloxy)acetophenone | Oakwood Chemical | MFCD03001269 | 244.265 | C15H13FO2 | 99.000 | CC(=O)c1ccccc1OCc1ccc(F)cc1 | 1g | 537671485
2'-(4-Fluorobenzyloxy)acetophenone | Oakwood Chemical | 400878-24-2 | MFCD03001269 | 244.265 | C15H13FO2 | 99.000 | CC(=O)c1ccccc1OCc1ccc(F)cc1 | 1g | 537671485
Gold Biotechnology Inc trans-Zeatin 50 mg
trans-Zeatin is a naturally occurring cytokinin plant growth regulator routinely used in plant tissue culture to induce cell division and shoot formation. trans-zeatin is freely soluble in acetic acid and water.
Medchemexpress LLC P-Hydroxycinnamic acid | 7400-08-0 | 100 G
p-Hydroxycinnamic acid is a common dietary phenol and ubiquitous plant metabolite that can inhibit platelet activity, thromboxane B2 production, and lipopolysaccharide-induced prostaglandin E2 generation. It also exhibits antioxidant and anti-inflammatory properties.
- Inhibits platelet activity.
- Inhibits thromboxane B2 production (IC50 of 371 μM).
- Inhibits lipopolysaccharide-induced prostaglandin E2 generation (IC50 of 126 μM).
- Possesses antioxidant properties.
- Possesses anti-inflammatory properties.
- Reduces ADP-induced platelet aggregation.
- Interferes with the arachidonic acid cascade.
- Has a purity of 99.94%.
Medchemexpress LLC Tyrphostin AG30 | 122520-79-0 | MFCD09739079 | 99.7% | 205.17 | C10H7NO4 | 1 ML
Tyrphostin AG30 (CAS 122520-79-0) is a small-molecule inhibitor of EGFR tyrosine kinase supplied as a 10 mM solution in DMSO (1 mL), intended for biochemical and cell-based research.
- Potent and selective EGFR tyrosine kinase inhibition.
- Supplied as a ready-to-use 10 mM solution in DMSO.
- High purity suitable for research applications.
- Molecular weight 205.17 and formula C10H7NO4 provided for characterization.
- Storage recommendations provided to maintain compound stability.
Medchemexpress LLC Tyrphostin AG1296 | 146535-11-7 | 99.7% | 266.29 | 25 MG
Tyrphostin AG1296 is a potent and selective inhibitor of platelet-derived growth factor receptor (PDGFR), with an IC50 of 0.8 μM. It inhibits signaling of human PDGF α- and β-receptors, as well as the related stem cell factor receptor (c-Kit). This compound is also a potent inhibitor of FLT3, with an IC50 in the micromolar range.
- Potent and selective inhibitor of platelet-derived growth factor receptor (PDGFR)
- Inhibits signaling of human PDGF α- and β-receptors
- Inhibits signaling of the related stem cell factor receptor (c-Kit)
- Potent inhibitor of FLT3
- Suppresses viability of PLX4032-resistant melanoma cells
- Induces apoptosis of A375R cells
- Inhibits PDGFR phosphorylation
- Suppresses A375R tumor growth in vivo
- Inhibits atherosclerotic plaque progression
![Medchemexpress LLC 2-[(3,4-dihydroxy-5-nitrophenyl)methylidene]propanedinitrile | 116313-73-6 | 98.7% | 231.16 g/mol | C10H5N3O4 | 10 MG](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000247968.png-250.jpg)
Medchemexpress LLC 2-[(3,4-dihydroxy-5-nitrophenyl)methylidene]propanedinitrile | 116313-73-6 | 98.7% | 231.16 g/mol | C10H5N3O4 | 10 MG
Tyrphostin AG 1288 is a small-molecule tyrosine kinase inhibitor used in research to block signaling pathways and reduce inflammatory responses, notably by inhibiting ICAM1 expression and TNFα-mediated cytotoxicity in vitro.
- Potent tyrosine kinase inhibitor.
- Inhibits ICAM1 expression and TNFα-mediated cytotoxicity in vitro.
- Molecular formula C10H5N3O4; molecular weight 231.16 g/mol.
- Purity 98.7% as supplied.
- Soluble ≥125 mg/mL (≈540.75 mM) in DMSO.
- Appearance solid, light yellow to yellow.
- Recommended storage: powder -20°C up to 3 years or 4°C up to 2 years; in solution -80°C up to 6 months or -20°C up to 1 month.
Medchemexpress LLC Tyrphostin A9 | 10537-47-0 | MFCD00209853 | 99.9% | 282.38 g/mol | C18H22N2O | 10 MG
Tyrphostin A9 is a small-molecule PDGFR inhibitor provided as an analytical standard for research applications. It is used in biochemical and cell-based studies to investigate tyrosine kinase signaling and mitochondrial dynamics. The material is supplied with purity and storage information and is available in multiple solid and solution formats for laboratory use.
- High purity suitable for analytical and research use.
- Useful as a PDGFR and tyrosine kinase inhibitor in cell and biochemical assays.
- Available in solid and solution formats for flexible experimental workflows.
- Documented stability when stored under recommended conditions.
- Supplied with supporting documentation such as a certificate of analysis or data sheet.
Medchemexpress LLC Tyrphostin A1 | 2826-26-8 | 98.96% | 184.19 | 50 MG
Tyrphostin A1 (AG9) inhibits CD40L-stimulated IL-12 production in macrophage cultures and antigen-induced generation of Th1 cells. It blocks CD40L-induced translocation of NF-κB to the nucleus and reduces the activation of the IL-12 p40 gene. In vivo therapy with A1 leads to a decrease in the generation of myelin basic protein (MBP) specific encephalitogenic T cells and attenuates experimental allergic encephalomyelitis (EAE) in SJL/J mice.
- Target: IL-12 production inhibitor
- Dose-dependent decrease of IL-12 p40, with maximal inhibition (62.5%) occurring at a dose of 10 μM
- Significantly weaker inhibitor of TK than other tyrphostins (IC50>1250 μM for epidermal growth factor receptor (EGFR) kinase)
- Useful for differentiating TK-mediated effects of tyrphostins from other non-specific effects